Source:http://linkedlifedata.com/resource/pubmed/id/18824462
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
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pubmed:dateCreated |
2008-11-17
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pubmed:databankReference | |
pubmed:abstractText |
Endothelial progenitor cells (EPCs) contribute to endothelial regeneration and thereby protect against cardiovascular disease (CVD). Patients with manifest CVD have reduced EPC levels, but it is not clear if this also occurs in subjects at high CVD risk without manifest atherosclerotic disease. Therefore, we aimed to first, measure circulating levels of EPCs in subjects without manifest CVD but at high cardiovascular risk due to obesity and presence of the metabolic syndrome. Second, we evaluated the effect on EPC levels of two lipid-lowering treatments.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1522-9645
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2808-17
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pubmed:dateRevised |
2010-9-14
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pubmed:meshHeading |
pubmed-meshheading:18824462-Anticholesteremic Agents,
pubmed-meshheading:18824462-Azetidines,
pubmed-meshheading:18824462-Cross-Over Studies,
pubmed-meshheading:18824462-Drug Therapy, Combination,
pubmed-meshheading:18824462-Endothelial Cells,
pubmed-meshheading:18824462-Endothelium, Vascular,
pubmed-meshheading:18824462-Humans,
pubmed-meshheading:18824462-Male,
pubmed-meshheading:18824462-Metabolic Syndrome X,
pubmed-meshheading:18824462-Middle Aged,
pubmed-meshheading:18824462-Obesity,
pubmed-meshheading:18824462-Postprandial Period,
pubmed-meshheading:18824462-Simvastatin,
pubmed-meshheading:18824462-Stem Cells
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pubmed:year |
2008
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pubmed:articleTitle |
Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy.
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pubmed:affiliation |
Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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