18823304

Source:http://linkedlifedata.com/resource/pubmed/id/18823304

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0031327, umls-concept:C0178602, umls-concept:C0246689, umls-concept:C0332464, umls-concept:C1280500, umls-concept:C1420131, umls-concept:C1514721, umls-concept:C1882417
pubmed:issue	6
pubmed:dateCreated	2008-11-26
pubmed:abstractText	To establish whether the effect of SLCO1B1[encoding organic anion transporting polypeptide 1B1 (OATP1B1)] c.521T-->C (p.Val174Ala) polymorphism on the pharmacokinetics of repaglinide is dose-dependent.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-11728565, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-12083976, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-12130747, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-12687332, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-12811365, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-12919179, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-14534525, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-15025742, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-15116054, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-15226675, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-15249516, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-15842561, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-15961978, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-16176562, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-16513447, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-16525793, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-16678545, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-16758257, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-16906022, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-17015053, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-17108811, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-17473846, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-18154446, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-18187595, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-18240907, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-18314419, http://linkedlifedata.com/resource/pubmed/commentcorrection/18823304-18388877
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7503323
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose, http://linkedlifedata.com/resource/pubmed/chemical/Carbamates, http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Organic Anion Transporters, http://linkedlifedata.com/resource/pubmed/chemical/Piperidines, http://linkedlifedata.com/resource/pubmed/chemical/SLCO1B1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/repaglinide
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	1365-2125
pubmed:author	pubmed-author:KalliokoskiAnnikkaA, pubmed-author:NeuvonenMikkoM, pubmed-author:NeuvonenPertti JPJ, pubmed-author:NiemiMikkoM
pubmed:issnType	Electronic
pubmed:volume	66
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	818-25
pubmed:dateRevised	2010-9-21
pubmed:meshHeading	pubmed-meshheading:18823304-Area Under Curve, pubmed-meshheading:18823304-Blood Glucose, pubmed-meshheading:18823304-Carbamates, pubmed-meshheading:18823304-Diabetes Mellitus, Type 2, pubmed-meshheading:18823304-Female, pubmed-meshheading:18823304-Genotype, pubmed-meshheading:18823304-Humans, pubmed-meshheading:18823304-Hypoglycemic Agents, pubmed-meshheading:18823304-Male, pubmed-meshheading:18823304-Metabolic Clearance Rate, pubmed-meshheading:18823304-Organic Anion Transporters, pubmed-meshheading:18823304-Piperidines, pubmed-meshheading:18823304-Polymorphism, Single Nucleotide, pubmed-meshheading:18823304-Young Adult
pubmed:year	2008
pubmed:articleTitle	The effect of SLCO1B1 polymorphism on repaglinide pharmacokinetics persists over a wide dose range.
pubmed:affiliation	Department of Clinical Pharmacology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't