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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-4-14
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pubmed:abstractText |
Real-time PCR has quantified decreased mitochondrial DNA levels in association with nucleoside reverse transcriptase inhibitor (NRTI) therapy of HIV-infected populations. However, real-time PCR is best suited to distinguish log differences in an analyte. In an effort to monitor individuals in more detail, we developed a flow cytometric assay to gauge mitochondrial function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1552-4957
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2008 Clinical Cytometry Society.
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pubmed:issnType |
Electronic
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
181-90
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pubmed:dateRevised |
2011-10-14
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pubmed:meshHeading |
pubmed-meshheading:18823003-Adenosine Triphosphatases,
pubmed-meshheading:18823003-Adult,
pubmed-meshheading:18823003-Child,
pubmed-meshheading:18823003-Child, Preschool,
pubmed-meshheading:18823003-DNA, Mitochondrial,
pubmed-meshheading:18823003-Dose-Response Relationship, Drug,
pubmed-meshheading:18823003-Electron Transport Complex IV,
pubmed-meshheading:18823003-Ethidium,
pubmed-meshheading:18823003-Flow Cytometry,
pubmed-meshheading:18823003-Humans,
pubmed-meshheading:18823003-Infant,
pubmed-meshheading:18823003-Leukocytes, Mononuclear,
pubmed-meshheading:18823003-Middle Aged,
pubmed-meshheading:18823003-Mitochondria,
pubmed-meshheading:18823003-Mitochondrial Proteins,
pubmed-meshheading:18823003-Reproducibility of Results,
pubmed-meshheading:18823003-Sensitivity and Specificity,
pubmed-meshheading:18823003-Young Adult,
pubmed-meshheading:18823003-Zalcitabine
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pubmed:year |
2009
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pubmed:articleTitle |
Assessment of mitochondrial toxicity by analysis of mitochondrial protein expression in mononuclear cells.
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pubmed:affiliation |
Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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