Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-9-29
pubmed:abstractText
Disability in multiple sclerosis is related to demyelination and axonal injury. Remyelination has been shown to occur in the different forms of the disease. In addition to restoring nerve conduction, myelin repair has a major role in preventing neurodegeneration. However, although sometimes extensive, remyelination is usually insufficient. Our understanding of the cellular and molecular mechanisms underlying the success or failure of myelin repair has benefited from lesion analysis in multiple sclerosis, and from in vivo and in vitro models of myelination and remyelination. This also provides potential targets for therapeutic intervention aimed at promoting endogenous remyelination.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0001-4079
pubmed:author
pubmed:issnType
Print
pubmed:volume
192
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
495-504; discussion 505-6
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
[Regenerative capacity in multiple sclerosis].
pubmed:affiliation
Fédération des maladies du système nerveux et Inserm U-711, Hôpital de la Salpêtrière, UPMC 47 boulevard de l'hôpital, 75651 Paris 13.
pubmed:publicationType
Journal Article, English Abstract, Review