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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-12-16
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pubmed:abstractText |
Most of the carcinogenic effects of polycyclic aromatic hydrocarbons present in tobacco smoke are mediated by the aryl hydrocarbon receptor (AHR), a ligand-dependent transcription factor that regulates tobacco-induced expression of carcinogen metabolic enzymes. We hypothesized that genetic variations in AHR might confer individual susceptibility to lung cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1744-6872
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pubmed:author |
pubmed-author:ChenDanD,
pubmed-author:FanWeiweiW,
pubmed-author:HuZhibinZ,
pubmed-author:HuangWeiW,
pubmed-author:LiuHongliangH,
pubmed-author:LiuYanhongY,
pubmed-author:LohWW,
pubmed-author:LuDaruD,
pubmed-author:MaHongxiaH,
pubmed-author:MiaoRuifenR,
pubmed-author:RIHAJJ,
pubmed-author:ShenHongbingH,
pubmed-author:SunWeiweiW,
pubmed-author:WangHaifengH,
pubmed-author:WangYiY,
pubmed-author:WeiQingyiQ,
pubmed-author:XXX
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-34
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pubmed:meshHeading |
pubmed-meshheading:18818557-Amino Acid Substitution,
pubmed-meshheading:18818557-Asian Continental Ancestry Group,
pubmed-meshheading:18818557-Case-Control Studies,
pubmed-meshheading:18818557-China,
pubmed-meshheading:18818557-Female,
pubmed-meshheading:18818557-Haplotypes,
pubmed-meshheading:18818557-Humans,
pubmed-meshheading:18818557-Linkage Disequilibrium,
pubmed-meshheading:18818557-Lung Neoplasms,
pubmed-meshheading:18818557-Male,
pubmed-meshheading:18818557-Middle Aged,
pubmed-meshheading:18818557-Pharmacogenetics,
pubmed-meshheading:18818557-Polymorphism, Single Nucleotide,
pubmed-meshheading:18818557-Receptors, Aryl Hydrocarbon,
pubmed-meshheading:18818557-Risk Factors,
pubmed-meshheading:18818557-Smoking
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pubmed:year |
2009
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pubmed:articleTitle |
Association of human aryl hydrocarbon receptor gene polymorphisms with risk of lung cancer among cigarette smokers in a Chinese population.
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pubmed:affiliation |
State Key Laboratory of Genetic Engineering and Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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