Linked Life Data

18817403

Source:http://linkedlifedata.com/resource/pubmed/id/18817403

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
21
pubmed:dateCreated
2008-10-30
pubmed:abstractText
The first total syntheses of racemic glyceollin I and its enantiomers are described. A Wittig approach was utilized as an entry to the appropriately substituted isoflav-3-ene so that an osmium tetroxide mediated asymmetric dihydroxylation could be deployed for stereospecific introduction of the 6a-hydroxy group. While using triphenylphosphine hydrobromide, a novel method was found for gently removing MOM from protected phenolic hydroxyl groups present within sensitive systems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1523-7052
pubmed:author
pubmed:issnType
Electronic
pubmed:day
6
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5007-10
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Total syntheses of racemic, natural (-) and unnatural (+) glyceollin I.
pubmed:affiliation
Department of Medicinal and Biological Chemistry, Center for Drug Design and Development, The University of Toledo, Toledo, Ohio 43606-3390, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.