Linked Life Data

18816074

Source:http://linkedlifedata.com/resource/pubmed/id/18816074

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2009-2-20
pubmed:abstractText
Fish is a major dietary source of potentially neurotoxic methylmercury compounds for humans. It is also a rich source of essential selenium. We have used in situ mercury L(III)-edge and selenium K-edge X-ray absorption spectroscopy to chemically characterize the methylmercury and selenium in both fresh fish and fish digested with simulated gastric fluid. For the mercury, we confirm our earlier finding [ Harris et al. ( 2003 ) Science 301 , 1203 ] that the methylmercury is coordinated by a single thiolate donor, which resembles cysteine, and for the selenium, we find a mixture of organic forms that resemble selenomethionine and an aliphatic selenenyl sulfide such as Cys-S-Se-Cys. We find that local chemical environments of mercury and selenium do not change upon digestion of the fish with simulated gastric fluid. We discuss the toxicological implications for humans consuming fish.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1520-5010
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2106-10
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Chemical forms of mercury and selenium in fish following digestion with simulated gastric fluid.
pubmed:affiliation
Department of Geological Sciences, University of Saskatchewan, 114 Science Place, Saskatoon, Saskatchewan S7N 5E2, Canada. g.george@usask.ca
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't