Source:http://linkedlifedata.com/resource/pubmed/id/18812736
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2008-9-24
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| pubmed:abstractText |
The use of pediatric ventricular assist devices (VADs) continues to evolve with the availability of smaller blood pumps. We examine the correlation of implanting appropriate sized blood pumps with a lower incidence of VAD related complications (VADRC). A 7-year retrospective review was undertaken for all pediatric VAD patients. Optimal VAD hemodynamics were defined as cardiac index of 2.7 L/m2 and rate of 80 beats per minute (bpm) with complete fill/empty of the blood pump. Patient/blood pump size match, VAD rate and fill/empty ratios were calculated (optimum = 1.0) and then correlated with incidence of VADRC. The study included 22 patients, mean age 9.77 years (6 mo-18 yrs) and mean body surface area (BSA) of 1.14 m2 (0.14 m2-2.32 m2), who underwent VAD implantation. VADRC included death while on support (n = 5), bleeding requiring reoperation (n = 8), hemolysis (n = 2), neurologic events (n = 2), thrombus formation (n = 3), and infection (n = 3). Six patients were bridged to transplant without any VADRC. This subset of patients had a mean blood pump size match ratio of 0.98, VAD rate ratio of 0.92 and fill/empty ratio of 1.00. Patients with VADRC (n = 16) were found to have a mean blood pump size match ratio of 0.72, VAD rate ratio of 0.72 and fill/empty ratio of 0.78. We report a series of pediatric patients with wide ranging BSA receiving VAD implantation. Selection of appropriate sized blood pumps can be correlated with decreased VADRC.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:issn |
1538-943X
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
54
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
474-8
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| pubmed:meshHeading |
pubmed-meshheading:18812736-Adolescent,
pubmed-meshheading:18812736-Child,
pubmed-meshheading:18812736-Child, Preschool,
pubmed-meshheading:18812736-Female,
pubmed-meshheading:18812736-Heart-Assist Devices,
pubmed-meshheading:18812736-Hemodynamics,
pubmed-meshheading:18812736-Humans,
pubmed-meshheading:18812736-Infant,
pubmed-meshheading:18812736-Male,
pubmed-meshheading:18812736-Population Groups,
pubmed-meshheading:18812736-Prosthesis Design,
pubmed-meshheading:18812736-Pulsatile Flow,
pubmed-meshheading:18812736-Retrospective Studies,
pubmed-meshheading:18812736-Treatment Outcome
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| pubmed:articleTitle |
Ventricular assist device implantation in the pediatric population: does pump size selection and associated hemodynamics impact outcomes?
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| pubmed:affiliation |
Department of Pediatrics, Congenital Heart Center, College of Medicine, University of Florida, Gainesville, Florida, USA. husain_adil@yahoo.com
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| pubmed:publicationType |
Journal Article
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