rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2008-11-26
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pubmed:abstractText |
Electroporation has been proved to enhance the efficacy of intramuscular delivery of DNA. However, the process of electroporation causes pain and discomfort to the patient receiving the treatment. Higher the electroporation voltages inflict greater pain, and this limits the circumstances in which the technique can be used clinically. The voltages generally used for electroporation in animals range from 100 to 1,200 V/cm. We studied the effect of DNA vaccination when electroporation was performed at lower voltages.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1423-0100
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2008 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
|
pubmed:volume |
51
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
241-6
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pubmed:meshHeading |
pubmed-meshheading:18812697-Animals,
pubmed-meshheading:18812697-Antibodies, Viral,
pubmed-meshheading:18812697-Body Weight,
pubmed-meshheading:18812697-Electroporation,
pubmed-meshheading:18812697-Hemagglutinin Glycoproteins, Influenza Virus,
pubmed-meshheading:18812697-Immunization, Secondary,
pubmed-meshheading:18812697-Influenza A Virus, H5N1 Subtype,
pubmed-meshheading:18812697-Influenza Vaccines,
pubmed-meshheading:18812697-Lung,
pubmed-meshheading:18812697-Mice,
pubmed-meshheading:18812697-Mice, Inbred BALB C,
pubmed-meshheading:18812697-Orthomyxoviridae Infections,
pubmed-meshheading:18812697-Survival Analysis,
pubmed-meshheading:18812697-Vaccines, DNA
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pubmed:year |
2008
|
pubmed:articleTitle |
Electroporation at low voltages enables DNA vaccine to provide protection against a lethal H5N1 avian influenza virus challenge in mice.
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pubmed:affiliation |
College of Life Sciences, Hunan Normal University, Changsha, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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