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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-10-3
pubmed:abstractText
Since the natural history of specific superficial femoral artery stenoses is not known, we examined progression rates of superficial femoral artery stenoses in 45 lower extremities found when arteriograms were obtained of 38 patients for symptomatic atherosclerotic disease in the opposite leg or abdomen. These initial superficial femoral artery arteriograms were compared with later arteriograms in 25 limbs, duplex scans in 27 limbs, and both modalities in 7 limbs. After a mean interval of 37 months, most superficial femoral artery stenoses (72%) did not progress. However, 12 superficial femoral artery stenoses progressed (28%; mean follow-up, 37 months, including 7 that occluded (17%). Superficial femoral artery stenoses progressed among patients who complained of symptom progression at a rate faster than that among asymptomatic patients (15.6%/year vs 3%/year; p = 0.006). Superficial femoral artery lesions also progressed more rapidly among patients whose contralateral superficial femoral artery was occluded (10%/year vs 1.6%/year; p = 0.04). By multivariate regression analysis, symptom progression and smoking history were predictive of superficial femoral artery stenosis progression. In the seven patients whose superficial femoral artery stenoses progressed to occlusion, the average rate of stenosis progression was 12%/year (maximum predicted rate, 30% per year by 95% confidence limit). These results indicate that superficial femoral artery stenoses usually progress with synchronous symptomatic deterioration. Other than symptom progression, only cumulative smoking history and contralateral superficial femoral artery occlusion could be associated with superficial femoral artery stenosis progression in this small series.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0741-5214
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
299-304
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:1880837-Aged, pubmed-meshheading:1880837-Aged, 80 and over, pubmed-meshheading:1880837-Aortic Aneurysm, pubmed-meshheading:1880837-Arterial Occlusive Diseases, pubmed-meshheading:1880837-Arteriosclerosis, pubmed-meshheading:1880837-Constriction, Pathologic, pubmed-meshheading:1880837-Diabetes Mellitus, Type 1, pubmed-meshheading:1880837-Female, pubmed-meshheading:1880837-Femoral Artery, pubmed-meshheading:1880837-Follow-Up Studies, pubmed-meshheading:1880837-Humans, pubmed-meshheading:1880837-Hypertension, pubmed-meshheading:1880837-Intermittent Claudication, pubmed-meshheading:1880837-Ischemia, pubmed-meshheading:1880837-Leg, pubmed-meshheading:1880837-Male, pubmed-meshheading:1880837-Methods, pubmed-meshheading:1880837-Middle Aged, pubmed-meshheading:1880837-Prognosis, pubmed-meshheading:1880837-Smoking, pubmed-meshheading:1880837-Time Factors
pubmed:year
1991
pubmed:articleTitle
The natural history of superficial femoral artery stenoses.
pubmed:affiliation
Section of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Hanover, NH 03756.
pubmed:publicationType
Journal Article