Linked Life Data

18804514

Source:http://linkedlifedata.com/resource/pubmed/id/18804514

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-10-22
pubmed:abstractText
We tend to simulate or recall others' appraisals through auditory verbal imagery (AVI) process to react appropriately. In particular, the ability to imagine derogatory appraisals by others may be critically important for social survival. In this study, we investigated the neural correlates implicated in the processing of unpleasant emotion related to derogatory remark and its self-directedness during AVI process. Twenty-three right-handed healthy human subjects participated in our study. We asked each subject to imagine hearing one's own or another person's voice saying derogatory or non-derogatory neutral remarks during the scanning of functional magnetic imaging. A test of the interaction between derogatory emotion and its self-directedness revealed significant activation of the amygdala. Additionally, we observed decreased neural activity in the anterior cingulate cortex (ACC) during imagery of derogatory remarks compared to neutral remarks. Our findings indicate an important role of the amygdala in the processing of unpleasant emotion or self-relevance of information in the real world may also be expanded to the processing of self-directedness of unpleasant emotion in the imagined world, and thereby contribute to human higher social cognitive process. This study also suggests that deactivation of ACC may enable us to enact vivid affective responses, and thereby contribute to an effective simulation of social interaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
446
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-6
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The role of amygdala during auditory verbal imagery of derogatory appraisals by others.
pubmed:affiliation
Department of Psychiatry, College of Medicine, Konyang University, 685, Gasoowon-Dong, Seo-Gu, Daejeon, Republic of Korea. cortex@konyang.ac.kr
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't