rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2008-9-17
|
pubmed:abstractText |
Association of the valine/methionine variant at codon 66 (Val66Met) of brain derived neurotrophic factor (BDNF) has been reported inconsistently across a spectrum of psychiatric disorders. Haplotypes of six tagging single nucleotide polymorphisms (SNPs) of a 37-kb region of dystrobrevin-binding protein 1 (DTNBP1) were found to be associated with schizophrenia. These haplotypes have not been studied extensively for other psychiatric disorders but are plausible candidates for anxiety and depression disorders. Here, association between variants of BDNF and DTNBP1, and multiple anxiety and depression phenotypes is explored.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1473-5873
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
219-25
|
pubmed:meshHeading |
pubmed-meshheading:18797396-Adult,
pubmed-meshheading:18797396-Anxiety,
pubmed-meshheading:18797396-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:18797396-Depression,
pubmed-meshheading:18797396-Dystrophin-Associated Proteins,
pubmed-meshheading:18797396-Gene Frequency,
pubmed-meshheading:18797396-Humans,
pubmed-meshheading:18797396-Linkage Disequilibrium,
pubmed-meshheading:18797396-Neuropeptides,
pubmed-meshheading:18797396-Neurotic Disorders,
pubmed-meshheading:18797396-Polymorphism, Single Nucleotide,
pubmed-meshheading:18797396-Spectrometry, Mass, Matrix-Assisted Laser...
|
pubmed:year |
2008
|
pubmed:articleTitle |
Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression.
|
pubmed:affiliation |
Queensland Institute of Medical Research, Brisbane, Australia. Naomi.Wray@qimr.edu.au
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Twin Study
|