Source:http://linkedlifedata.com/resource/pubmed/id/18797358
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-9-17
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pubmed:abstractText |
Patients with malignant brain astrocytomas are at high risk for developing hyperglycemia secondary to frequent corticosteroid administration. Several clinical studies have shown that hyperglycemia is associated with poor outcome in multiple disease states. Furthermore, hyperglycemia augments in vitro astrocytoma growth, whereas hypoglycemia attenuates in vitro astrocytoma cell growth. We hypothesized that persistent hyperglycemic states in the outpatient setting may serve as a prognostic marker of decreased survival in patients with malignant brain astrocytomas.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1524-4040
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
286-91; discussion 291
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pubmed:meshHeading |
pubmed-meshheading:18797358-Adult,
pubmed-meshheading:18797358-Aged,
pubmed-meshheading:18797358-Ambulatory Care,
pubmed-meshheading:18797358-Astrocytoma,
pubmed-meshheading:18797358-Brain Neoplasms,
pubmed-meshheading:18797358-Craniotomy,
pubmed-meshheading:18797358-Follow-Up Studies,
pubmed-meshheading:18797358-Humans,
pubmed-meshheading:18797358-Hyperglycemia,
pubmed-meshheading:18797358-Middle Aged,
pubmed-meshheading:18797358-Neurosurgical Procedures,
pubmed-meshheading:18797358-Retrospective Studies,
pubmed-meshheading:18797358-Survival Rate
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pubmed:year |
2008
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pubmed:articleTitle |
Persistent outpatient hyperglycemia is independently associated with decreased survival after primary resection of malignant brain astrocytomas.
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pubmed:affiliation |
Department of Neurosurgery, Johns Hopkins School of Medicine, and The Johns Hopkins Neuro-oncology Surgical Outcomes Research Laboratory, Baltimore, Maryland, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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