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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-3
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pubmed:dateCreated |
2008-11-25
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pubmed:abstractText |
Bosentan, an endothelin (ET) ETA-ETB receptors antagonist, is an effective therapy for idiopathic pulmonary arterial hypertension (PAH) and for PAH related to connective tissue disease (CTD). The aim of this study was to evaluate the behaviour of ET-1 and brain natriuretic peptide (BNP) venous plasma levels during a 6-month dual ET-1 receptor blockade and the potential influence of baseline ET-1 venous plasma levels on the clinical efficacy of bosentan.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0167-0115
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pubmed:author |
pubmed-author:BadagliaccaRobertoR,
pubmed-author:BenedettiGiuliaG,
pubmed-author:CrescenziEleonoraE,
pubmed-author:FedeleFrancescoF,
pubmed-author:FerranteFabioF,
pubmed-author:LetiziaClaudioC,
pubmed-author:NonaAlfredA,
pubmed-author:PetramalaLuigiL,
pubmed-author:PosciaRobertoR,
pubmed-author:SciomerSusannaS,
pubmed-author:VizzaCarmine DarioCD,
pubmed-author:ZepponiEnricoE
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pubmed:issnType |
Print
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pubmed:day |
29
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pubmed:volume |
151
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
48-53
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pubmed:meshHeading |
pubmed-meshheading:18796317-Adult,
pubmed-meshheading:18796317-Antihypertensive Agents,
pubmed-meshheading:18796317-Endothelin-1,
pubmed-meshheading:18796317-Female,
pubmed-meshheading:18796317-Humans,
pubmed-meshheading:18796317-Hypertension, Pulmonary,
pubmed-meshheading:18796317-Male,
pubmed-meshheading:18796317-Middle Aged,
pubmed-meshheading:18796317-Natriuretic Peptide, Brain,
pubmed-meshheading:18796317-Receptor, Endothelin A,
pubmed-meshheading:18796317-Sulfonamides,
pubmed-meshheading:18796317-Time Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Venous endotelin-1 (ET-1) and brain natriuretic peptide (BNP) plasma levels during 6-month bosentan treatment for pulmonary arterial hypertension.
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pubmed:affiliation |
Dept. Cardiovascular and Respiratory Science, Italy.
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pubmed:publicationType |
Journal Article
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