rdf:type |
|
lifeskim:mentions |
umls-concept:C0008059,
umls-concept:C0021655,
umls-concept:C0028754,
umls-concept:C0202098,
umls-concept:C0205082,
umls-concept:C0205314,
umls-concept:C0205419,
umls-concept:C0205653,
umls-concept:C0314603,
umls-concept:C0679622,
umls-concept:C1970415
|
pubmed:issue |
11
|
pubmed:dateCreated |
2008-11-17
|
pubmed:abstractText |
The global prevalence of obesity and overweight is increasing rapidly among adults as well as among children and adolescents. Recent genome-wide association studies have provided strong support for association between variants in the FTO gene and obesity. We sequenced regions of the FTO gene to identify novel variants that are associated with obesity and related metabolic traits.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1476-5497
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1730-5
|
pubmed:dateRevised |
2009-9-15
|
pubmed:meshHeading |
pubmed-meshheading:18794893-Adolescent,
pubmed-meshheading:18794893-Blood Glucose,
pubmed-meshheading:18794893-Body Mass Index,
pubmed-meshheading:18794893-Child,
pubmed-meshheading:18794893-Female,
pubmed-meshheading:18794893-Genetic Predisposition to Disease,
pubmed-meshheading:18794893-Genetic Variation,
pubmed-meshheading:18794893-Genome-Wide Association Study,
pubmed-meshheading:18794893-Humans,
pubmed-meshheading:18794893-Insulin Resistance,
pubmed-meshheading:18794893-Male,
pubmed-meshheading:18794893-Obesity,
pubmed-meshheading:18794893-Phenotype,
pubmed-meshheading:18794893-Polymorphism, Single Nucleotide,
pubmed-meshheading:18794893-Young Adult
|
pubmed:year |
2008
|
pubmed:articleTitle |
Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents.
|
pubmed:affiliation |
Department of Neuroscience, Functional Pharmacology, Uppsala University, Uppsala, Sweden.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|