Source:http://linkedlifedata.com/resource/pubmed/id/18793457
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2008-9-16
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pubmed:abstractText |
In this paper we present preliminary results stemming from a novel application of Markov Models and Support Vector Machines to splice site classification of Intron-Exon and Exon-Intron (5' and 3') splice sites. We present the use of Markov based statistical methods, in a log likelihood discriminator framework, to create a non-summed, fixed-length, feature vector for SVM-based classification. We also explore the use of Shannon-entropy based analysis for automated identification of minimal-size models (where smaller models have known information loss according to the specified Shannon entropy representation). We evaluate a variety of kernels and kernel parameters in the classification effort. We present results of the algorithms for splice-site datasets consisting of sequences from a variety of species for comparison.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2105
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
9 Suppl 9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S12
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pubmed:dateRevised |
2010-9-21
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pubmed:meshHeading |
pubmed-meshheading:18793457-Algorithms,
pubmed-meshheading:18793457-Artificial Intelligence,
pubmed-meshheading:18793457-Data Interpretation, Statistical,
pubmed-meshheading:18793457-Markov Chains,
pubmed-meshheading:18793457-Pattern Recognition, Automated,
pubmed-meshheading:18793457-Sequence Analysis,
pubmed-meshheading:18793457-Stochastic Processes
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pubmed:year |
2008
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pubmed:articleTitle |
Hybrid MM/SVM structural sensors for stochastic sequential data.
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pubmed:affiliation |
Department of Computer Science, University of New Orleans, LA 70148, USA. broux@cs.uno.edu
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pubmed:publicationType |
Journal Article
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