Linked Life Data

1879254

Source:http://linkedlifedata.com/resource/pubmed/id/1879254

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-10-2
pubmed:abstractText
Oral administration of Yin Zhi Huang (YZH) daily for 3 days in rabbits accelerated plasma clearance of infused unconjugated bilirubin. A similar but less dramatic effect resulted from 3 days pretreatment with phenobarbital, 70 mg/kg/day orally. Similar doses were injected intraperitoneally in rats for 3 days, following which the bile ducts were ligated and bilirubin infused intravenously. Plasma clearance of unconjugated bilirubin and plasma appearance of conjugated bilirubin were faster, and hepatic bilirubin content was higher in both YZH- and phenobarbital-treated rats than in control animals. These observations indicate that YZH is as effective as phenobarbital in stimulating bilirubin metabolic pathways and suggest that the drugs may share common mechanisms of action.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0379-8305
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-64
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Effect of a traditional Chinese medicine, yin zhi huang, on bilirubin clearance and conjugation.
pubmed:affiliation
Department of Pediatrics, Second Affiliated Hospital, Hunan Medical University, Changsha, PRC.
pubmed:publicationType
Journal Article, Comparative Study