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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2008-10-3
pubmed:abstractText
SUMMARY:: Broad sharp waves (BSWs) are a rarely recognized EEG pattern, defined as focal or lateralized high voltage, biphasic, sharply contoured 0.5 to 1/sec waves distinguished from background activities by exceeding their voltage for at least two times. The aim of the study was to determine EEG criteria, frequency, and clinical significance of BSWs. During a 2-year period, we prospectively gathered EEG records exhibiting BSWs in a large EEG laboratory of a university hospital. Clinical variables and the relationship to epileptic seizures were analyzed. Forty-eight (0.6% of 7569) patients exhibited BSWs. In 38 (79%) patients, they were localized over the frontal region. In 31 (65%) patients, no spikes or sharp waves have been recorded. Thirty-four (71%) patients underwent previous neurosurgical interventions. All but one patient suffered one or more epileptic seizures corresponding to a positive predictive value of BSWs for seizures of 98%. A symptomatic etiology of the seizures, i.e., head trauma, brain tumor, aneurysm clipping after subarachnoid hemorrhage, and stroke could be established in all but two patients. In four patients, seizures have been classified as acute symptomatic, in 43 (86%) patients remote symptomatic epilepsy was diagnosed, and in 38 (79%) patients of frontal lobe origin. Broad sharp waves can be considered as an epileptiform EEG pattern on its own. Furthermore, BSWs are an indicator for acute and/or remote cerebral lesions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1537-1603
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
250-4
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Broad sharp waves-an underrecognized EEG pattern in patients with epileptic seizures.
pubmed:affiliation
Departments of Neurology, Medical University Innsbruck, Innsbruck, Austria. gerhard.bauer@i-med.ac.at
pubmed:publicationType
Journal Article