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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-9-15
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pubmed:abstractText |
We have previously shown that the anti-neoplastic agent erucylphosphohomocholine (ErPC3) requires the mitochondrial 18 kDa Translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor (PBR), to induce cell death via the mitochondrial apoptosis pathway.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4'-chlorodiazepam,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Benzodiazepinones,
http://linkedlifedata.com/resource/pubmed/chemical/Caspases,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochromes c,
http://linkedlifedata.com/resource/pubmed/chemical/Erucic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Isoquinolines,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Mitochondrial Membrane Transport...,
http://linkedlifedata.com/resource/pubmed/chemical/PK 11195,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphorylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, GABA,
http://linkedlifedata.com/resource/pubmed/chemical/TSPO protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/erucylphosphohomocholine ErPC3,
http://linkedlifedata.com/resource/pubmed/chemical/mitochondrial permeability...
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pubmed:status |
MEDLINE
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pubmed:issn |
1570-5870
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
435-50
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pubmed:meshHeading |
pubmed-meshheading:18791274-Antineoplastic Agents,
pubmed-meshheading:18791274-Apoptosis,
pubmed-meshheading:18791274-Benzodiazepinones,
pubmed-meshheading:18791274-Blotting, Western,
pubmed-meshheading:18791274-Caspases,
pubmed-meshheading:18791274-Cell Line, Tumor,
pubmed-meshheading:18791274-Cell Proliferation,
pubmed-meshheading:18791274-Cytochromes c,
pubmed-meshheading:18791274-Erucic Acids,
pubmed-meshheading:18791274-Glioblastoma,
pubmed-meshheading:18791274-Humans,
pubmed-meshheading:18791274-Isoquinolines,
pubmed-meshheading:18791274-Ligands,
pubmed-meshheading:18791274-Membrane Potential, Mitochondrial,
pubmed-meshheading:18791274-Mitochondrial Membrane Transport Proteins,
pubmed-meshheading:18791274-Phosphorylcholine,
pubmed-meshheading:18791274-Receptors, GABA
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pubmed:year |
2008
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pubmed:articleTitle |
Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine.
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pubmed:affiliation |
Abteilung Pädiatrie I, Zentrum Kinderheilkunde und Jugendmedizin, Universitätsklinikum Göttingen, D-37075 Göttingen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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