|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0013216,
umls-concept:C0030705,
umls-concept:C0034802,
umls-concept:C0205179,
umls-concept:C0205195,
umls-concept:C0332293,
umls-concept:C0597360,
umls-concept:C0684249,
umls-concept:C0936012,
umls-concept:C1122962,
umls-concept:C1514162,
umls-concept:C1696465
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2009-2-2
|
|
pubmed:abstractText |
Two large, randomized, placebo-controlled trials (IRESSA NSCLC Trial Assessing Combination Therapy; INTACT 1 and 2) in non-small-cell lung cancer (NSCLC) failed to show survival benefit for gefitinib (IRESSA) in combination with first-line platinum-based chemotherapy. Epidermal growth factor receptor (EGFR) staining was assessed retrospectively in relation to survival response to gefitinib in combination with chemotherapy.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1432-1335
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
135
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
467-76
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:18787840-Antineoplastic Agents,
pubmed-meshheading:18787840-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:18787840-Biopsy,
pubmed-meshheading:18787840-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:18787840-Cell Division,
pubmed-meshheading:18787840-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18787840-Humans,
pubmed-meshheading:18787840-Immunohistochemistry,
pubmed-meshheading:18787840-Lung Neoplasms,
pubmed-meshheading:18787840-Neoplasm Staging,
pubmed-meshheading:18787840-Placebos,
pubmed-meshheading:18787840-Platinum Compounds,
pubmed-meshheading:18787840-Prognosis,
pubmed-meshheading:18787840-Quinazolines,
pubmed-meshheading:18787840-Receptor, Epidermal Growth Factor,
pubmed-meshheading:18787840-Survival Analysis
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Epidermal growth factor receptor expression analysis in chemotherapy-naive patients with advanced non-small-cell lung cancer treated with gefitinib or placebo in combination with platinum-based chemotherapy.
|
|
pubmed:affiliation |
Free University Medical Center, Amsterdam, The Netherlands. giacconeg@mail.nih.gov
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
