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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2008-10-28
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pubmed:abstractText |
Peroxisome Proliferator-Activated Receptors (PPARs) and its co-activators are regulatory elements of the cellular lipid homeostasis and have been associated with feeding behavior modulation. Animal models suggest that these genes may be involved in alcohol consumption regulation. However, no studies in humans exist. Our aim is to estimate the possible association between polymorphisms in the PPAR-alpha, PPAR-gamma and PPAR-gamma co-activator 1A (PGC-1A) genes and alcohol consumption in humans.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0009-8981
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
398
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
70-4
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pubmed:meshHeading |
pubmed-meshheading:18786524-Adolescent,
pubmed-meshheading:18786524-Adult,
pubmed-meshheading:18786524-Aged,
pubmed-meshheading:18786524-Aged, 80 and over,
pubmed-meshheading:18786524-Alcohol Drinking,
pubmed-meshheading:18786524-Alleles,
pubmed-meshheading:18786524-Cross-Sectional Studies,
pubmed-meshheading:18786524-DNA,
pubmed-meshheading:18786524-Female,
pubmed-meshheading:18786524-Gene Frequency,
pubmed-meshheading:18786524-Genotype,
pubmed-meshheading:18786524-Heat-Shock Proteins,
pubmed-meshheading:18786524-Humans,
pubmed-meshheading:18786524-Male,
pubmed-meshheading:18786524-Mediterranean Region,
pubmed-meshheading:18786524-Middle Aged,
pubmed-meshheading:18786524-PPAR alpha,
pubmed-meshheading:18786524-Polymorphism, Genetic,
pubmed-meshheading:18786524-Polymorphism, Single Nucleotide,
pubmed-meshheading:18786524-Socioeconomic Factors,
pubmed-meshheading:18786524-Spain,
pubmed-meshheading:18786524-Transcription Factors,
pubmed-meshheading:18786524-Young Adult
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pubmed:year |
2008
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pubmed:articleTitle |
PPAR-alpha L162V and PGC-1 G482S gene polymorphisms, but not PPAR-gamma P12A, are associated with alcohol consumption in a Spanish Mediterranean population.
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pubmed:affiliation |
Department of Preventive and Legal Medicine, School of Medicine, University of Valencia, Valencia, Spain. francesc.frances@uv.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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