Linked Life Data

18785437

Source:http://linkedlifedata.com/resource/pubmed/id/18785437

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-9-12
pubmed:abstractText
The triad of anorectal malformation, a sacrococcygeal defect, and a presacral mass was first described by Kennedy in 1926. Currarino et al recognized these disorders as a syndrome in 1981. The Currarino syndrome (CS) belongs to the group of neurenteric malformations and is associated with chronic constipation. The presacral mass generally is a teratoma or an anterior meningocele. The anorectal malformation either is anal stenosis or agenesis. The 3 anomalies characterizing this syndrome can be ascribed to a common developmental defect or anomaly of the notochord in the early phases of embryogenesis. Currant genetic studies implicate mutations in gene HLXB9 for the autosomal dominant inherited character of the syndrome in about 50% of the patients. A rare case of Currarino syndrome is presented as a first one in our practice with the diagnostic and therapeutic problems and review of the literature.
pubmed:language
bul
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0450-2167
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-60
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
[Currarino syndrome--a case report].
pubmed:publicationType
Journal Article, English Abstract, Case Reports