18785005

Source:http://linkedlifedata.com/resource/pubmed/id/18785005

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0004083, umls-concept:C0021665, umls-concept:C0043157, umls-concept:C0043210, umls-concept:C0175630, umls-concept:C0279752, umls-concept:C0441889, umls-concept:C1334089, umls-concept:C1519302, umls-concept:C1846502, umls-concept:C2598146
pubmed:issue	2
pubmed:dateCreated	2009-6-15
pubmed:abstractText	Results from several studies indicate that mammographic density, a strong risk factor for breast cancer, is greater in premenopausal women with higher circulating IGF-I levels. Both mammographic density and circulating IGF-I levels appear to be partly heritable traits. We hypothesized that in premenopausal women, IGF1 variants are associated with circulating IGF-I concentration, which in turn influences variation in breast density. Therefore, we examined the association of IGF1 polymorphisms with circulating IGF-I levels and mammographic density.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8111104
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor I
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1573-7217
pubmed:author	pubmed-author:BoydNorman FNF, pubmed-author:FehringerGordonG, pubmed-author:KnightJulia AJA, pubmed-author:OzcelikHilmiH, pubmed-author:PatersonAndrew DAD
pubmed:issnType	Electronic
pubmed:volume	116
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	413-23
pubmed:meshHeading	pubmed-meshheading:18785005-Adult, pubmed-meshheading:18785005-Anthropometry, pubmed-meshheading:18785005-Body Composition, pubmed-meshheading:18785005-Breast, pubmed-meshheading:18785005-Breast Neoplasms, pubmed-meshheading:18785005-European Continental Ancestry Group, pubmed-meshheading:18785005-Female, pubmed-meshheading:18785005-Genetic Predisposition to Disease, pubmed-meshheading:18785005-Genotype, pubmed-meshheading:18785005-Haplotypes, pubmed-meshheading:18785005-Humans, pubmed-meshheading:18785005-Insulin-Like Growth Factor I, pubmed-meshheading:18785005-Linkage Disequilibrium, pubmed-meshheading:18785005-Mammography, pubmed-meshheading:18785005-Microsatellite Repeats, pubmed-meshheading:18785005-Middle Aged, pubmed-meshheading:18785005-Polymerase Chain Reaction, pubmed-meshheading:18785005-Polymorphism, Genetic, pubmed-meshheading:18785005-Premenopause, pubmed-meshheading:18785005-Radioimmunoassay, pubmed-meshheading:18785005-Risk Factors
pubmed:year	2009
pubmed:articleTitle	Association between IGF1 CA microsatellites and mammographic density, anthropometric measures, and circulating IGF-I levels in premenopausal Caucasian women.
pubmed:affiliation	Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada. gordon.fehringer@cancercare.on.ca
pubmed:publicationType	Journal Article