Linked Life Data

18783724

Source:http://linkedlifedata.com/resource/pubmed/id/18783724

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-3-23
pubmed:abstractText
Mass-action epidemic models are the foundation of the majority of studies of disease dynamics in human and animal populations. Here, a kinetic model of mobile susceptible and infective individuals in a two-dimensional domain is introduced, and an examination of the contact process results in a mass-action-like term for the generation of new infectives. The conditions under which density dependent and frequency dependent transmission terms emerge are clarified. Moreover, this model suggests that epidemics in large mobile spatially distributed populations can be well described by homogeneously mixing mass-action models. The analysis generates an analytic formula for the contact rate (beta) and the basic reproductive ratio (R0) of an infectious pathogen, which contains a mixture of demographic and epidemiological parameters. The analytic results are compared with a simulation and are shown to give good agreement. The simulation permits the exploration of more realistic movement strategies and their consequent effect on epidemic dynamics.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0025-5564
pubmed:author
pubmed:issnType
Print
pubmed:volume
216
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
56-62
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Contact rate calculation for a basic epidemic model.
pubmed:affiliation
Institute for Mathematical Sciences, Imperial College London, 53 Prince's Gate, Exhibition Road, South Kensington, London SW7 2PG, UK. c.rhodes@imperial.ac.uk
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't