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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2009-1-21
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pubmed:abstractText |
The major drawback of stent implantation in native human coronary vessels is the occurrence of restenosis. Drug-eluting stents significantly reduce restenosis after percutaneous coronary intervention (PCI), but may be associated with persistent local inflammation involved in the restenosis mechanisms. In this setting coating coronary devices with anti-inflammatory agents represents an intriguing alternative to stent-based local drug delivery. The aim of the present study was to test in a porcine model the safety and efficacy of a novel Genistein-eluting balloon preceding coronary stenting.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1861-0692
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
891-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18777002-Angioplasty, Balloon,
pubmed-meshheading:18777002-Angioplasty, Balloon, Coronary,
pubmed-meshheading:18777002-Animals,
pubmed-meshheading:18777002-Anti-Inflammatory Agents,
pubmed-meshheading:18777002-Coronary Restenosis,
pubmed-meshheading:18777002-Disease Models, Animal,
pubmed-meshheading:18777002-Drug-Eluting Stents,
pubmed-meshheading:18777002-Endothelium, Vascular,
pubmed-meshheading:18777002-Female,
pubmed-meshheading:18777002-Genistein,
pubmed-meshheading:18777002-Hyperplasia,
pubmed-meshheading:18777002-Inflammation,
pubmed-meshheading:18777002-Random Allocation,
pubmed-meshheading:18777002-Stents,
pubmed-meshheading:18777002-Swine,
pubmed-meshheading:18777002-Time Factors,
pubmed-meshheading:18777002-Tunica Intima
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pubmed:year |
2008
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pubmed:articleTitle |
Effect of a novel drug-eluted balloon coated with genistein before stent implantation in porcine coronary arteries.
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pubmed:affiliation |
Interventional Cardiology, Division of Cardiology, University of Turin, San Giovanni Battista Hospital, Turin, Italy. isheiban@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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