Linked Life Data

18776581

Source:http://linkedlifedata.com/resource/pubmed/id/18776581

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
52
pubmed:dateCreated
2008-9-8
pubmed:abstractText
Naphthalenediimide (1) carrying two beta-cyclodextrins (beta CDs) was successfully synthesized by click chemistry between pentynylnaphthalenediimide and azido beta CD. Absorption spectra of 1 showed hypochromic and red shifts upon addition of sonicated calf thymus DNA as a double stranded DNA. Kinetic studies showed its slow association with and dissociation from calf thymus DNA. These results suggested that 1 can bind to double stranded DNA by the threading mode, where one of the beta CD is required to go through adjacent base pairs of double stranded DNA. If this is proven, beta CD is one of the largest groups ever reported which can go through a DNA duplex for threading.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1746-8272
pubmed:author
pubmed:issnType
Electronic
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
717-8
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Synthesis of naphthalenediimide having two beta-cyclodextrins at both of its substituent termini.
pubmed:affiliation
Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu 804-8550, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't