Linked Life Data

18776418

Source:http://linkedlifedata.com/resource/pubmed/id/18776418

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
52
pubmed:dateCreated
2008-9-8
pubmed:abstractText
Previously, we established a new strategy of synchronous cross linking reaction activated by hybridization to target genes. In this strategy, the highly reactive cross-linking agent, 2-amino-6-vinylpurine nucleoside analog, is generated from its stable precursors by a hybridization-promoted activation process with selectivity to cytosine. In this paper, we wish to report the synthesis of the peptide nucleic acids (PNAs) incorporating 2-amino-6-vinylpurine derivatives and the evaluation of their reactivity to target DNA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1746-8272
pubmed:author
pubmed:issnType
Electronic
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
391-2
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Synthesis of the peptide nucleic acid (PNA) incorporating 2-amino-6-vinylpurine derivative and evaluation of the reactivity.
pubmed:affiliation
Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai-Shi, Miyagi, Japan.
pubmed:publicationType
Journal Article