Source:http://linkedlifedata.com/resource/pubmed/id/18776328
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
52
|
| pubmed:dateCreated |
2008-9-8
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| pubmed:abstractText |
In this report, we show the recognition of RNA secondary structure by exploiting a fluorescent 2,7-disubstituted 9H-xanthen-9-one derivative (2). The xanthone derivertive (2) especially bound to RNA and became non-fluorescent. Upon mixing with RRE model RNA, U-bulge RNA, or hairpin RNA, the fluorescence intensity of 2 was decreased in different intensity. The distinct fluorescent increase of 2 to each RNA seems to a good probe for The RNA structures.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
1746-8272
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
211-2
|
| pubmed:meshHeading | |
| pubmed:year |
2008
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| pubmed:articleTitle |
Fluorescent ligand as a molecular probe for the RNA structure.
|
| pubmed:affiliation |
The institute of Scientific and Industrial Reserch, Osaka University, Mihogaoka 8-1, Ibaraki 567-0047, Japan.
|
| pubmed:publicationType |
Journal Article
|