Source:http://linkedlifedata.com/resource/pubmed/id/18774716
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
19
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pubmed:dateCreated |
2008-9-23
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pubmed:abstractText |
This paper describes a series of modifications of the side chain of micromolide, an anti-tuberculosis natural product. Most of the synthesized compounds showed significantly decreased activities, which suggests that the long aliphatic side chain of micromolide and its double bond are essential to its activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1464-3405
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5311-5
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18774716-Alkenes,
pubmed-meshheading:18774716-Antitubercular Agents,
pubmed-meshheading:18774716-Biological Agents,
pubmed-meshheading:18774716-Combinatorial Chemistry Techniques,
pubmed-meshheading:18774716-Lactones,
pubmed-meshheading:18774716-Molecular Structure,
pubmed-meshheading:18774716-Plants, Medicinal,
pubmed-meshheading:18774716-Structure-Activity Relationship,
pubmed-meshheading:18774716-Tuberculosis
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pubmed:year |
2008
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pubmed:articleTitle |
Modification of the side chain of micromolide, an anti-tuberculosis natural product.
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pubmed:affiliation |
Drug Discovery Program, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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