Linked Life Data

18772023

Source:http://linkedlifedata.com/resource/pubmed/id/18772023

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-9-5
pubmed:abstractText
Vascular assembly, patterning, and maintenance is a complex and highly regulated process that begins with the formation of a primary capillary plexus by means of angiogenesis or vasculogenesis and ends when the primitive vessels have been remodeled into quiescent, differentiated vessels. Differentiated or "mature" microvessels are characterized in large part by their association with pericytes, and failure of these interactions results in severe, and often lethal, defects that have been implicated in a number of human pathologic conditions, including tumor angiogenesis, diabetic microangiopathy, ectopic tissue calcification, stroke, and dementia. This chapter describes methods that can be used to isolate and culture primary pericytes, as well as to study pericyte-endothelial cell interactions with in vitro cell culture systems.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1557-7988
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
443
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
315-31
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Pericyte isolation and use in endothelial/pericyte coculture models.
pubmed:affiliation
Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural