Linked Life Data

18768161

Source:http://linkedlifedata.com/resource/pubmed/id/18768161

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-11-10
pubmed:abstractText
Plants use phytochrome (phy) photoreceptors to detect and respond to changes in the quantities and proportions of red (R) and far-red (FR) light in their environments. The principal mediators of responses to R and FR in Arabidopsis thaliana are phyA and phyB, which are found in all angiosperms surveyed. The present study is concerned with a phytochrome gene pair in Arabidopsis, PHYB and PHYD, which are of relatively recent origin, share high sequence identity, and are partially redundant. Our data suggest that the duplication occurred after the mustard family (Brassicaceae) diverged from its closest relatives but before the radiation of extant Brassicaceae, and that both copies have persisted for up to 40myr. We detected no evidence of positive selection in the divergence of PHYD from PHYB; the evolution of both sequences is constrained by purifying selection. Levels of diversity at both loci are among the lowest observed at nuclear genes in A. thaliana. In common with other loci in A. thaliana, PHYB and PHYD showed elevated levels of intraspecific replacement variation, and each showed an excess of rare nucleotide polymorphisms, consistent with a recent, rapid population expansion. Our results are consistent with the functional importance of amino acid divergence in the central regions of phyB and phyD and suggest specific sites for mutagenesis that may yield insights into the functional differences of phyB and phyD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1095-9513
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
411-23
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Phylogenetic relationships of B-related phytochromes in the Brassicaceae: Redundancy and the persistence of phytochrome D.
pubmed:affiliation
Arnold Arboretum of Harvard University, 22 Divinity Avenue, Cambridge, MA 02138, USA. smathews@oeb.harvard.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't