18765525

Source:http://linkedlifedata.com/resource/pubmed/id/18765525

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0034786, umls-concept:C0037083, umls-concept:C0086418, umls-concept:C0162638, umls-concept:C0332206, umls-concept:C0334227, umls-concept:C0376358, umls-concept:C1522496, umls-concept:C1524003, umls-concept:C1710082
pubmed:issue	17
pubmed:dateCreated	2008-9-3
pubmed:abstractText	beta2-Microglobulin (beta2M) has been shown to promote osteomimicry and the proliferation of human prostate cancer cells. The objective of this study is to determine the mechanism by which targeting beta2M using anti-beta2M antibody inhibited growth and induced apoptosis in prostate cancer cells.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/P01 CA098912-06, http://linkedlifedata.com/resource/pubmed/grant/P01 CA098912-07, http://linkedlifedata.com/resource/pubmed/grant/P01 CA098912-08, http://linkedlifedata.com/resource/pubmed/grant/P01 CA98912, http://linkedlifedata.com/resource/pubmed/grant/R01 CA122602-03, http://linkedlifedata.com/resource/pubmed/grant/U54 CA119338
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, http://linkedlifedata.com/resource/pubmed/chemical/Prostate-Specific Antigen, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Androgen, http://linkedlifedata.com/resource/pubmed/chemical/beta 2-Microglobulin
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	1078-0432
pubmed:author	pubmed-author:ChuChia-YiCY, pubmed-author:ChungLeland W KLW, pubmed-author:HavelJonathan JJJ, pubmed-author:HuangWen-ChinWC, pubmed-author:LueHui-WenHW, pubmed-author:NomuraTakeoT, pubmed-author:QianWei PingWP, pubmed-author:ZhauHaiyen EHE
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	14
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	5341-7
pubmed:dateRevised	2011-7-22
pubmed:meshHeading	pubmed-meshheading:18765525-Antibodies, pubmed-meshheading:18765525-Apoptosis, pubmed-meshheading:18765525-Cell Line, Tumor, pubmed-meshheading:18765525-Cell Proliferation, pubmed-meshheading:18765525-Gene Expression Regulation, Neoplastic, pubmed-meshheading:18765525-Humans, pubmed-meshheading:18765525-Male, pubmed-meshheading:18765525-Neoplasms, Hormone-Dependent, pubmed-meshheading:18765525-Prostate-Specific Antigen, pubmed-meshheading:18765525-Prostatic Neoplasms, pubmed-meshheading:18765525-Receptors, Androgen, pubmed-meshheading:18765525-Signal Transduction, pubmed-meshheading:18765525-beta 2-Microglobulin
pubmed:year	2008
pubmed:articleTitle	Beta2-microglobulin signaling blockade inhibited androgen receptor axis and caused apoptosis in human prostate cancer cells.
pubmed:affiliation	Molecular Urology and Therapeutics Program, Department of Urology and Winship Cancer Institute, Emory University School of Medicine, GA 30322, USA. whuang3@emory.edu
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, N.I.H., Extramural