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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
38
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pubmed:dateCreated |
2008-9-19
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pubmed:abstractText |
We described here a coumarin-based dual-excitation ratiometric probe for cadmium, CadMQ. This fluorescence sensor has high quantum yields of 0.59 and 0.70 in the metal-free and Cd2+-bound forms, respectively, and has a dissociation constant of 0.16 nM for Cd2+. CadMQ is cell permeable and locates within the acidic compartments of the cells. We further show that CadMQ is a useful tool to ratiometrically probe the change in the intracellular Cd2+ levels with the use of two excited wavelengths.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1520-5126
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:day |
24
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
12564-5
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pubmed:meshHeading |
|
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pubmed:year |
2008
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pubmed:articleTitle |
Fluorescence imaging of intracellular cadmium using a dual-excitation ratiometric chemosensor.
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pubmed:affiliation |
Graduate School of Human and Environmental Studies, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. taki@chem.mbox.media.kyoto-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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