|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002085,
umls-concept:C0010592,
umls-concept:C0021201,
umls-concept:C0022646,
umls-concept:C0035015,
umls-concept:C0332281,
umls-concept:C0376622,
umls-concept:C0444956,
umls-concept:C0450127,
umls-concept:C1514873,
umls-concept:C1548437,
umls-concept:C1709269,
umls-concept:C1882923
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|
pubmed:issue |
7
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|
pubmed:dateCreated |
2008-9-1
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|
pubmed:abstractText |
Interindividual heterogeneity in expression of ABCB1 gene has been suspected to be one of the factors resulting in cyclosporin (CsA) pharmacokinetic variation. The present study explored the association of ABCB1 SNPs on CsA dose requirements and dose-adjusted C2 levels (CsA level/daily dose requirement) in renal allograft recipients.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0188-4409
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
39
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
695-701
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18760199-Adolescent,
pubmed-meshheading:18760199-Adult,
pubmed-meshheading:18760199-Alleles,
pubmed-meshheading:18760199-Cyclosporine,
pubmed-meshheading:18760199-Female,
pubmed-meshheading:18760199-Gene Frequency,
pubmed-meshheading:18760199-Genotype,
pubmed-meshheading:18760199-Graft Rejection,
pubmed-meshheading:18760199-Haplotypes,
pubmed-meshheading:18760199-Humans,
pubmed-meshheading:18760199-Immunosuppressive Agents,
pubmed-meshheading:18760199-India,
pubmed-meshheading:18760199-Kaplan-Meier Estimate,
pubmed-meshheading:18760199-Kidney Transplantation,
pubmed-meshheading:18760199-Male,
pubmed-meshheading:18760199-Middle Aged,
pubmed-meshheading:18760199-P-Glycoprotein,
pubmed-meshheading:18760199-Polymorphism, Single Nucleotide,
pubmed-meshheading:18760199-Transplantation, Homologous
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|
pubmed:year |
2008
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pubmed:articleTitle |
ABCB1 G2677 allele is associated with high dose requirement of cyclosporin A to prevent renal allograft rejection in North India.
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|
pubmed:affiliation |
Department of Urology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow, Uttar Pradesh, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
