rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9
|
pubmed:dateCreated |
2008-9-1
|
pubmed:abstractText |
Over the past 10 years, healthcare providers involved in the management of metastatic colorectal cancer (MCRC) have seen an explosion in new agents and their combinations. These developments have resulted in an expansion in the options of care for MCRC patients and in a significant improvement in their overall survival. This article reviews the current role of anti-EGFR monoclonal antibodies in the management of MCRC and the identification of recent markers of response that lead towards treatment individualization.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Camptothecin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/bevacizumab,
http://linkedlifedata.com/resource/pubmed/chemical/cetuximab,
http://linkedlifedata.com/resource/pubmed/chemical/irinotecan,
http://linkedlifedata.com/resource/pubmed/chemical/panitumumab
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pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1744-8328
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1471-80
|
pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18759698-Antibodies, Monoclonal,
pubmed-meshheading:18759698-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:18759698-Antineoplastic Agents,
pubmed-meshheading:18759698-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:18759698-Camptothecin,
pubmed-meshheading:18759698-Colorectal Neoplasms,
pubmed-meshheading:18759698-Drug Resistance, Neoplasm,
pubmed-meshheading:18759698-Humans,
pubmed-meshheading:18759698-Neoplasm Metastasis,
pubmed-meshheading:18759698-Receptor, Epidermal Growth Factor
|
pubmed:year |
2008
|
pubmed:articleTitle |
Anti-EGFR monoclonal antibodies in metastatic colorectal cancer: time for an individualized approach?
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pubmed:affiliation |
Roswell Park Cancer Institute, Buffalo, NY 14263, USA. marwan.fakih@roswellpark.org
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pubmed:publicationType |
Journal Article,
Review
|