Source:http://linkedlifedata.com/resource/pubmed/id/18759333
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2008-10-7
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pubmed:abstractText |
Two new xanthones, 8-(methoxycarbonyl)-1-hydroxy-9-oxo-9H-xanthene-3-carboxylic acid (1) and dimethyl 8-methoxy-9-oxo-9H-xanthene-1,6-dicarboxylate (2) and one known xanthone methyl 8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate (3) were isolated from the culture broth of the mangrove fungus Penicillium sp. (ZZF 32#) collected from the South China Sea. Their structures were established by comprehensive analysis of one-dimensional (1D) and two-dimensional (2D) NMR data. The structure of compound 3 was confirmed by X-ray crystallography, which led to the suggestion that janthinone (4) might have the same structure as 3. Compounds 1-3 were inactive against KB or KBv200 cells during cytotoxicity evaluations.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1097-458X
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pubmed:author | |
pubmed:copyrightInfo |
2008 John Wiley & Sons, Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1066-9
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pubmed:meshHeading |
pubmed-meshheading:18759333-Cell Line, Tumor,
pubmed-meshheading:18759333-Cell Survival,
pubmed-meshheading:18759333-China,
pubmed-meshheading:18759333-Crystallography, X-Ray,
pubmed-meshheading:18759333-Humans,
pubmed-meshheading:18759333-Molecular Structure,
pubmed-meshheading:18759333-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:18759333-Penicillium,
pubmed-meshheading:18759333-Xanthones
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pubmed:year |
2008
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pubmed:articleTitle |
Structure elucidation of two new xanthone derivatives from the marine fungus Penicillium sp. (ZZF 32#) from the South China Sea.
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pubmed:affiliation |
School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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