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rdf:type |
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lifeskim:mentions |
umls-concept:C0018099,
umls-concept:C0030705,
umls-concept:C0034656,
umls-concept:C0041931,
umls-concept:C0087111,
umls-concept:C0137914,
umls-concept:C0178602,
umls-concept:C0205390,
umls-concept:C0301630,
umls-concept:C0439064,
umls-concept:C0729830,
umls-concept:C1274040,
umls-concept:C2350656,
umls-concept:C2603343
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pubmed:issue |
9
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pubmed:dateCreated |
2008-9-8
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pubmed:databankReference |
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pubmed:abstractText |
To assess the efficacy of pegloticase in achieving and maintaining plasma urate levels of <6 mg/dl in gout patients in whom other treatments have failed, and to assess the pharmacokinetics and safety of pegloticase.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1529-0131
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2882-91
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pubmed:meshHeading |
pubmed-meshheading:18759308-Adult,
pubmed-meshheading:18759308-Aged,
pubmed-meshheading:18759308-Dose-Response Relationship, Drug,
pubmed-meshheading:18759308-Drug Administration Schedule,
pubmed-meshheading:18759308-Female,
pubmed-meshheading:18759308-Gout,
pubmed-meshheading:18759308-Humans,
pubmed-meshheading:18759308-Intention to Treat Analysis,
pubmed-meshheading:18759308-Male,
pubmed-meshheading:18759308-Middle Aged,
pubmed-meshheading:18759308-Patient Selection,
pubmed-meshheading:18759308-Polyethylene Glycols,
pubmed-meshheading:18759308-Treatment Outcome,
pubmed-meshheading:18759308-Urate Oxidase,
pubmed-meshheading:18759308-Uric Acid
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pubmed:year |
2008
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pubmed:articleTitle |
Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: results of a phase II randomized study.
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pubmed:affiliation |
Duke University Medical Center, Durham, North Carolina 27710, USA. john.sundy@duke.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
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