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rdf:type |
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lifeskim:mentions |
umls-concept:C0012634,
umls-concept:C0026336,
umls-concept:C0026339,
umls-concept:C0035820,
umls-concept:C0086418,
umls-concept:C0137833,
umls-concept:C0158266,
umls-concept:C0591833,
umls-concept:C1817330,
umls-concept:C2607943,
umls-concept:C2926606
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pubmed:issue |
9
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pubmed:dateCreated |
2008-9-8
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pubmed:abstractText |
Runx2 is a transcription factor that regulates chondrocyte differentiation. This study was undertaken to address the role of the different Runx proteins (Runx1, Runx2, or Runx3) in chondrocyte differentiation using chondrocyte-specific Runx-transgenic mice, and to study the importance of the QA domain of Runx2, which is involved in its transcriptional activation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1529-0131
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pubmed:author |
pubmed-author:AeKeisukeK,
pubmed-author:AsouYoshinoriY,
pubmed-author:FukumotoSeijiS,
pubmed-author:HaroHirotakaH,
pubmed-author:JinnoTetsuyaT,
pubmed-author:KarsentyGerardG,
pubmed-author:KawaguchiHiroshiH,
pubmed-author:KimuraAyakoA,
pubmed-author:LiuXiuyunX,
pubmed-author:MiyazakiMakikoM,
pubmed-author:OsakiMitsuhikoM,
pubmed-author:OzdemirJerfiJ,
pubmed-author:SatoShingoS,
pubmed-author:ShinomiyaKen-IchiK,
pubmed-author:TakedaShuS,
pubmed-author:TakeuchiYasuhiroY
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pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2764-75
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18759297-Animals,
pubmed-meshheading:18759297-Autoradiography,
pubmed-meshheading:18759297-Bone Diseases,
pubmed-meshheading:18759297-Bone and Bones,
pubmed-meshheading:18759297-Calcinosis,
pubmed-meshheading:18759297-Cartilage,
pubmed-meshheading:18759297-Cell Differentiation,
pubmed-meshheading:18759297-Chondrocytes,
pubmed-meshheading:18759297-Chondrogenesis,
pubmed-meshheading:18759297-Core Binding Factor alpha Subunits,
pubmed-meshheading:18759297-Gene Expression Regulation, Developmental,
pubmed-meshheading:18759297-Humans,
pubmed-meshheading:18759297-Immunohistochemistry,
pubmed-meshheading:18759297-In Situ Hybridization,
pubmed-meshheading:18759297-Intervertebral Disc,
pubmed-meshheading:18759297-Intervertebral Disc Degeneration,
pubmed-meshheading:18759297-Mice,
pubmed-meshheading:18759297-Mice, Transgenic,
pubmed-meshheading:18759297-RNA, Messenger,
pubmed-meshheading:18759297-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18759297-Time Factors,
pubmed-meshheading:18759297-Weight-Bearing
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pubmed:year |
2008
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pubmed:articleTitle |
The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: findings in murine models and in human disease.
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pubmed:affiliation |
Tokyo Medical and Dental University, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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