Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-10-17
pubmed:abstractText
Females of many animal species store sperm for taxon-specific periods of time, ranging from a few hours to years. Female sperm storage has important reproductive and evolutionary consequences, yet relatively little is known of its molecular basis. Here, we report the isolation of a loss-of-function mutation of the Drosophila melanogaster Acp29AB gene, which encodes a seminal fluid protein that is transferred from males to females during mating. Using this mutant, we show that Acp29AB is required for the normal maintenance of sperm in storage. Consistent with this role, Acp29AB localizes to female sperm storage organs following mating, although it does not appear to associate tightly with sperm. Acp29AB is a predicted lectin, suggesting that sugar-protein interactions may be important for D. melanogaster sperm storage, much as they are in many mammals. Previous association studies have found an effect of Acp29AB genotype on a male's sperm competitive ability; our findings suggest that effects on sperm storage may underlie these differences in sperm competition. Moreover, Acp29AB's effects on sperm storage and sperm competition may explain previously documented evidence for positive selection on the Acp29AB locus.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-10353898, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-10511561, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-10511562, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-10612039, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-10885514, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-11061424, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-11181560, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-11369612, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-11805057, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-12071887, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-12424377, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-12679097, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-12939382, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-13929245, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-14718510, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-14758086, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-15166147, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-15215320, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-15345744, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-15374649, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-15466425, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-15888732, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-15979005, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-16388004, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-16612885, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-16736526, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-16790686, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-16910995, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-16914271, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17247158, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17276455, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17435238, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17452049, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17479456, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17573377, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17711815, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17715429, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-17720900, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-18077584, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-18085830, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-18245332, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-2257979, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-3124270, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-3142802, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-3620562, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-6030948, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-6210197, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-6790342, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-7543298, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-7705622, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-7707978, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-7711750, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-8367469, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-8527509, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-8587107, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-9014340, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-9160719, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-9474779, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-9537986, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-9784973, http://linkedlifedata.com/resource/pubmed/commentcorrection/18757944-9880253
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0016-6731
pubmed:author
pubmed:issnType
Print
pubmed:volume
180
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
921-31
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
More...