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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
25
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pubmed:dateCreated |
2008-9-1
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pubmed:databankReference |
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pubmed:abstractText |
The majority of gastrointestinal stromal tumors (GIST) can be cured by surgery alone, but relapse occurs in 20% to 40% of cases. GISTs are considered to invariably arise through gain of function KIT or PDGFA mutation of the interstitial cells of Cajal (ICC). However, the genetic basis of the malignant progression of GISTs are poorly understood.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:HasegawaTadashiT,
pubmed-author:HirohashiSetsuoS,
pubmed-author:HondaKazufumiK,
pubmed-author:IchikawaHitoshiH,
pubmed-author:KawaiAkiraA,
pubmed-author:KuwabaraHideyaH,
pubmed-author:NakayamaRobertR,
pubmed-author:OnoMasayaM,
pubmed-author:SakumaTomohiroT,
pubmed-author:SasakoMitsuruM,
pubmed-author:ShimadaYasuhiroY,
pubmed-author:ShimodaTadakazuT,
pubmed-author:ShitashigeMikiM,
pubmed-author:ShojiAyakoA,
pubmed-author:YamadaTesshiT,
pubmed-author:YamaguchiUmioU
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4100-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18757323-Cluster Analysis,
pubmed-meshheading:18757323-Coiled Bodies,
pubmed-meshheading:18757323-Dipeptidyl Peptidase 4,
pubmed-meshheading:18757323-Gastrointestinal Stromal Tumors,
pubmed-meshheading:18757323-Gene Expression Profiling,
pubmed-meshheading:18757323-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18757323-Humans,
pubmed-meshheading:18757323-Immunohistochemistry,
pubmed-meshheading:18757323-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18757323-Platelet-Derived Growth Factor,
pubmed-meshheading:18757323-Prognosis,
pubmed-meshheading:18757323-Proto-Oncogene Proteins c-kit,
pubmed-meshheading:18757323-Recurrence,
pubmed-meshheading:18757323-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18757323-Tumor Markers, Biological
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pubmed:year |
2008
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pubmed:articleTitle |
Distinct gene expression-defined classes of gastrointestinal stromal tumor.
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pubmed:affiliation |
Chemotherapy Division and Cancer Proteomics Project, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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