Source:http://linkedlifedata.com/resource/pubmed/id/18756541
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
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| pubmed:dateCreated |
2008-10-1
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| pubmed:abstractText |
A 21-year-old man with homozygous sickle cell disease maintained on hydroxyurea for 1 year developed thrombosis of the superior sagittal, right transverse, and right sigmoid dural sinuses with a large venous infarct. He was successfully treated with endovascular thrombolysis. Investigation did not reveal any inherited or acquired hypercoagulable state. This patient however had consistently elevated hemoglobin levels both at the time of the initial event and on follow up. One year later he developed symptomatic avascular necrosis of the right hip. High hemoglobin levels resulting from hydroxyurea therapy may have contributed to development of complications in this patient.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Oct
|
| pubmed:issn |
1096-8652
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2008 Wiley-Liss, Inc.
|
| pubmed:issnType |
Electronic
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| pubmed:volume |
83
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
818-20
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| pubmed:meshHeading |
pubmed-meshheading:18756541-Adult,
pubmed-meshheading:18756541-Anemia, Sickle Cell,
pubmed-meshheading:18756541-Antisickling Agents,
pubmed-meshheading:18756541-Brain Infarction,
pubmed-meshheading:18756541-Dura Mater,
pubmed-meshheading:18756541-Follow-Up Studies,
pubmed-meshheading:18756541-Hemoglobins,
pubmed-meshheading:18756541-Hip,
pubmed-meshheading:18756541-Homozygote,
pubmed-meshheading:18756541-Humans,
pubmed-meshheading:18756541-Hydroxyurea,
pubmed-meshheading:18756541-Male,
pubmed-meshheading:18756541-Osteonecrosis,
pubmed-meshheading:18756541-Sinus Thrombosis, Intracranial,
pubmed-meshheading:18756541-Stroke,
pubmed-meshheading:18756541-Thrombolytic Therapy,
pubmed-meshheading:18756541-Time Factors,
pubmed-meshheading:18756541-Treatment Outcome
|
| pubmed:year |
2008
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| pubmed:articleTitle |
Venous sinus thrombosis leading to stroke in a patient with sickle cell disease on hydroxyurea and high hemoglobin levels: treatment with thrombolysis.
|
| pubmed:affiliation |
Department of Radiology, American University of Beirut Medical Center, Beirut, Lebanon.
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| pubmed:publicationType |
Journal Article,
Case Reports
|