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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-2-27
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pubmed:abstractText |
In experimental nephropathies, inhibitors of the renin-angiotensin-system (RAS) halted the progression, or even induced a regression in renal injury. We studied the potential of the angiotensin-converting enzyme (ACE) inhibitor perindopril and the angiotensin receptor blocker candesartan to reverse the established renal injury in the obese Zucker rat (OZR).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1421-9670
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pubmed:author |
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pubmed:copyrightInfo |
2008 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
164-70
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pubmed:meshHeading |
pubmed-meshheading:18753741-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:18753741-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:18753741-Animals,
pubmed-meshheading:18753741-Benzimidazoles,
pubmed-meshheading:18753741-Blood Pressure,
pubmed-meshheading:18753741-Body Weight,
pubmed-meshheading:18753741-Diabetic Nephropathies,
pubmed-meshheading:18753741-Kidney Function Tests,
pubmed-meshheading:18753741-Kidney Glomerulus,
pubmed-meshheading:18753741-Male,
pubmed-meshheading:18753741-Organ Size,
pubmed-meshheading:18753741-Oxidative Stress,
pubmed-meshheading:18753741-Perindopril,
pubmed-meshheading:18753741-Proteinuria,
pubmed-meshheading:18753741-Random Allocation,
pubmed-meshheading:18753741-Rats,
pubmed-meshheading:18753741-Rats, Zucker,
pubmed-meshheading:18753741-Tetrazoles
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pubmed:year |
2009
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pubmed:articleTitle |
Functional and partial morphological regression of established renal injury in the obese zucker rat by blockade of the renin-angiotensin system.
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pubmed:affiliation |
Department of Clinical and Experimental Pharmacotherapy, Slovak Medical University, Bratislava, Slovakia. katarina.sebekova@szu.sk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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