Single or small groups of dedifferentiated tumor cells, referred to as tumor budding, may be found ahead of the defined invasive edge of colorectal carcinomas. Tumor budding is claimed to correlate with lymph node metastasis and local recurrence.
Gastrointestinal and Liver Pathology Research Laboratory, Department of Pathology, Karolinska Institute and University Hospital, 17176, Stockholm, Sweden. Carlos.Rubio@ki.se
