Source:http://linkedlifedata.com/resource/pubmed/id/18728577
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2008-8-27
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pubmed:abstractText |
The complement cascade has been implicated in cerebral ischemia/reperfusion injury. To develop clinically useful therapies that successfully manipulate the complement cascade, the individual roles of its components must be clearly defined. Previous studies have shown that C5 inhibition improves outcome after experimental stroke. In this study, we investigated the role of C5a in stroke injury by inhibiting its activity at the receptor level.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1524-4040
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
122-5; discussion 125-6
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pubmed:meshHeading |
pubmed-meshheading:18728577-Animals,
pubmed-meshheading:18728577-Brain Ischemia,
pubmed-meshheading:18728577-Complement C5a,
pubmed-meshheading:18728577-Male,
pubmed-meshheading:18728577-Mice,
pubmed-meshheading:18728577-Mice, Inbred C57BL,
pubmed-meshheading:18728577-Peptides,
pubmed-meshheading:18728577-Receptor, Anaphylatoxin C5a,
pubmed-meshheading:18728577-Reperfusion Injury,
pubmed-meshheading:18728577-Stroke
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pubmed:year |
2008
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pubmed:articleTitle |
Protective effect of C5a receptor inhibition after murine reperfused stroke.
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pubmed:affiliation |
Department of Neurological Surgery, Columbia University, New York, New York 10032, USA. ghkim9@yahoo.com
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pubmed:publicationType |
Journal Article,
Comparative Study
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