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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-8-4
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pubmed:abstractText |
Adult-onset schizophrenia has repeatedly been associated with disturbances in the temporal lobes and alterations in cortical folding, which are thought to reflect neurodevelopmental impairment. Early-onset schizophrenia (EOS; onset before 18 years) is considered to involve even more pronounced neurodevelopmental deviance across a wide range of brain structural measures. We hypothesized that overall alteration of cortical folding also applies to EOS, and EOS involves prominent structural aberrations in superior temporal and collateral sulci.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1527-5418
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1125-32
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pubmed:meshHeading |
pubmed-meshheading:18725863-Adolescent,
pubmed-meshheading:18725863-Age Factors,
pubmed-meshheading:18725863-Antipsychotic Agents,
pubmed-meshheading:18725863-Cerebral Cortex,
pubmed-meshheading:18725863-Child,
pubmed-meshheading:18725863-Dominance, Cerebral,
pubmed-meshheading:18725863-Female,
pubmed-meshheading:18725863-Humans,
pubmed-meshheading:18725863-Image Processing, Computer-Assisted,
pubmed-meshheading:18725863-Imaging, Three-Dimensional,
pubmed-meshheading:18725863-Lissencephaly,
pubmed-meshheading:18725863-Magnetic Resonance Imaging,
pubmed-meshheading:18725863-Male,
pubmed-meshheading:18725863-Psychiatric Status Rating Scales,
pubmed-meshheading:18725863-Reference Values,
pubmed-meshheading:18725863-Schizophrenia,
pubmed-meshheading:18725863-Schizophrenic Psychology,
pubmed-meshheading:18725863-Sex Factors,
pubmed-meshheading:18725863-Temporal Lobe,
pubmed-meshheading:18725863-Young Adult
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pubmed:year |
2008
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pubmed:articleTitle |
Global and temporal cortical folding in patients with early-onset schizophrenia.
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pubmed:affiliation |
Research Unit Neuroimaging & Psychiatry U797, Institut National de la Santé et de la Recherche Médicale, IFR49, Orsay, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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