Source:http://linkedlifedata.com/resource/pubmed/id/18724288
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
2008-8-25
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| pubmed:abstractText |
In 1998, the Tunisian team of the 'Centre National de Greffe de Moelle Osseuse' initiated allogeneic hematopoietic SCT (AHSCT) in Tunisia. As of June 2007, information was collected about 299 patients with a first AHSCT and 12 additional retransplants. The median age was 19 years (range 2-49 years). The main indications were aplastic anemia (n=106, 36%), leukemia and nonmalignant disorders (n=153, 51%), Fanconi anemia (n=26, 9%) and other nonmalignant disorders (n=14, 4%). Preparative regimens depended on indication. All donors were HLA geno-identical. The stem cell sources were BM (87%) and PBSCs (13%). At the time of analysis, 200 patients (67%) were alive after a median follow-up of 42 months (range 3-112 months). The overall TRM rate was 17%. Outcome depended on indication. According to our results, allogeneic HSCT is potentially curative for hematological diseases, but it is a toxic approach for malignant disorders.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Aug
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| pubmed:issn |
0268-3369
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
42 Suppl 1
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
S139-S141
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| pubmed:meshHeading | |
| pubmed:year |
2008
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| pubmed:articleTitle |
Allogeneic hematopoietic stem cell transplantation in Tunisia.
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| pubmed:affiliation |
Hematology Department, Centre National de Greffe de Moelle Osseuse de Tunis, Tunis, Tunisia. benothman-t@mailcity.com
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| pubmed:publicationType |
Journal Article
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