rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4-6
|
pubmed:dateCreated |
2008-11-10
|
pubmed:abstractText |
Potassium channels are important in pulmonary circulation because they have been closely related to hypoxic pulmonary vasoconstriction (HPV). The objective of the study was to determine whether structural changes in pulmonary arteries (PA), such as those observed in patients with chronic obstructive pulmonary disease (COPD), might be associated with changes in the mRNA expression of both BK(Ca) and K(V) channels and their potential relationship with HPV.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1537-1891
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
49
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
178-84
|
pubmed:meshHeading |
pubmed-meshheading:18723123-Aged,
pubmed-meshheading:18723123-Anoxia,
pubmed-meshheading:18723123-Blotting, Western,
pubmed-meshheading:18723123-Charybdotoxin,
pubmed-meshheading:18723123-Endothelium, Vascular,
pubmed-meshheading:18723123-Histamine,
pubmed-meshheading:18723123-Humans,
pubmed-meshheading:18723123-Immunochemistry,
pubmed-meshheading:18723123-Male,
pubmed-meshheading:18723123-Middle Aged,
pubmed-meshheading:18723123-Muscle, Smooth, Vascular,
pubmed-meshheading:18723123-Norepinephrine,
pubmed-meshheading:18723123-Potassium Channels, Calcium-Activated,
pubmed-meshheading:18723123-Potassium Chloride,
pubmed-meshheading:18723123-Pulmonary Artery,
pubmed-meshheading:18723123-Pulmonary Disease, Chronic Obstructive,
pubmed-meshheading:18723123-RNA, Messenger,
pubmed-meshheading:18723123-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18723123-Tunica Intima,
pubmed-meshheading:18723123-Vasoconstriction
|
pubmed:articleTitle |
Expression of BK(Ca) channels in human pulmonary arteries: relationship with remodeling and hypoxic pulmonary vasoconstriction.
|
pubmed:affiliation |
Departments of Pulmonary Medicine and Pathology, Ciber de Enfermedades Respiratorias, Hospital Clínic, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain. vpeinado@clinic.ub.es
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|