Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2008-10-22
pubmed:abstractText
Dry coating is an innovative powder-layering technique that enables the formation of coatings on solid dosage forms with no need for using water or organic solvents. This technique envisages the distribution of polymer powder blends onto substrate cores and the concurrent or alternate nebulization of liquid plasticizers. In this work, a dry coating process based on hydroxypropyl methylcellulose acetate succinate (HPMCAS) was set up in a rotary fluid bed equipment to prepare enteric-coated soft gelatin capsules. Promising results were obtained in terms of process feasibility and product characteristics, thus suggesting the possibility of advantageous applications for the investigated technique when dealing with gelatin capsule substrates.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1520-5762
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1196-200
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Dry coating of soft gelatin capsules with HPMCAS.
pubmed:affiliation
Istituto di Chimica Farmaceutica e Tossicologica "P. Pratesi", Universita degli Studi di Milano, Milan, Italy. matteo.cerea@unimi.it
pubmed:publicationType
Journal Article, Comparative Study