Source:http://linkedlifedata.com/resource/pubmed/id/18716896
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2009-5-27
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pubmed:abstractText |
PARP-1 plays important role in the BER (base excision repair) and maintenance of genomic integrity. Previous study found the Val762Ala genetic variant in the PARP-1 gene contributed to susceptibility of some cancers and decreased PARP-1 enzyme activity in response to oxidative damage. Helicobacter pylori (H. pylori) infection was thought to be one of the major causes of gastric cancer. In this study, we investigated the association between the PARP-1 Val762Ala polymorphism, CagA(+) H. pylori infection, and the risk for gastric cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1573-4978
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1461-7
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pubmed:meshHeading |
pubmed-meshheading:18716896-Amino Acid Substitution,
pubmed-meshheading:18716896-Analysis of Variance,
pubmed-meshheading:18716896-Case-Control Studies,
pubmed-meshheading:18716896-China,
pubmed-meshheading:18716896-Genetic Predisposition to Disease,
pubmed-meshheading:18716896-Genotype,
pubmed-meshheading:18716896-Helicobacter Infections,
pubmed-meshheading:18716896-Humans,
pubmed-meshheading:18716896-Poly(ADP-ribose) Polymerases,
pubmed-meshheading:18716896-Polymerase Chain Reaction,
pubmed-meshheading:18716896-Polymorphism, Genetic,
pubmed-meshheading:18716896-Risk,
pubmed-meshheading:18716896-Stomach Neoplasms
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pubmed:year |
2009
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pubmed:articleTitle |
PARP-1 Val762Ala polymorphism, CagA+ H. pylori infection and risk for gastric cancer in Han Chinese population.
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pubmed:affiliation |
Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou, 730000, China.
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pubmed:publicationType |
Journal Article
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