18714339

Source:http://linkedlifedata.com/resource/pubmed/id/18714339

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0005516, umls-concept:C0035647, umls-concept:C1416877, umls-concept:C1527249
pubmed:issue	8
pubmed:dateCreated	2008-8-20
pubmed:abstractText	A-type lamins are type V intermediate filament proteins encoded by the gene LMNA. Mutations in LMNA give rise to diverse degenerative diseases related to premature ageing. A-type lamins also influence the activity of the Retinoblastoma protein (pRb) and oncogenes such a beta-catenin. Consequently, it has been speculated that expression of A-type lamins may also influence tumour progression.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101285081
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers, http://linkedlifedata.com/resource/pubmed/chemical/LMNA protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Lamin Type A, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological, http://linkedlifedata.com/resource/pubmed/chemical/lamin C
pubmed:status	MEDLINE
pubmed:issn	1932-6203
pubmed:author	pubmed-author:CoxThomas RTR, pubmed-author:HutchisonChristopher JCJ, pubmed-author:PrzyborskiStefan ASA, pubmed-author:Rahman-CasañsSyed FSF, pubmed-author:SmitsKimK, pubmed-author:WeijenbergMattyM, pubmed-author:WillisNaomi DND, pubmed-author:WilsonRobert GRG, pubmed-author:de BruïneAdriaanA, pubmed-author:van EngelandManonM, pubmed-author:van den BrandtPietP
pubmed:issnType	Electronic
pubmed:volume	3
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e2988
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:18714339-Adult, pubmed-meshheading:18714339-Alternative Splicing, pubmed-meshheading:18714339-Biological Markers, pubmed-meshheading:18714339-Cell Death, pubmed-meshheading:18714339-Colon, pubmed-meshheading:18714339-Colonic Neoplasms, pubmed-meshheading:18714339-Colorectal Neoplasms, pubmed-meshheading:18714339-Gene Expression Regulation, Neoplastic, pubmed-meshheading:18714339-Humans, pubmed-meshheading:18714339-Lamin Type A, pubmed-meshheading:18714339-Prognosis, pubmed-meshheading:18714339-Risk Assessment, pubmed-meshheading:18714339-Tumor Markers, Biological
pubmed:year	2008
pubmed:articleTitle	Lamin A/C is a risk biomarker in colorectal cancer.
pubmed:affiliation	School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom.
pubmed:publicationType	Journal Article

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